Dipeptidyl Peptidase-4/DPP-4 Inhibitors and Biguanide Antidiabetic Combinations

Dipeptidyl peptidase-4/DPP-4 inhibitors and biguanide antidiabetic combinations are a form of hypoglycemic used to treat diabetes mellitus type 2. DPP-4 inhibitors block DPP-4, increasing incretin levels and inhibiting glucagon release. Biguanide antidiabetics improve the body's sensitivity to insulin and reduce the amount of sugar absorbed by the intestines. A commonly used dipeptidyl peptidase-4/DPP-4 inhibitors and biguanide antidiabetic combination is Janumet (sitagliptin, metformin, hydrochloride).

Drugs classified as Dipeptidyl Peptidase-4/DPP-4 Inhibitors and Biguanide Antidiabetic Combinations are frequently used to treat the following conditions:

• type 2 diabetes mellitus

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