Idiopathic pulmonary fibrosis is a chronic lung disease characterized by the unexplained buildup of scar tissue in the lungs, causing a progressive decline in lung function and shortness of breath. Around 48,000 people in the United States are diagnosed with idiopathic pulmonary fibrosis each year. 

Symptoms of idiopathic pulmonary fibrosis include a dry non-productive cough, shortness of breath while exercising, swollen fingertips or toes, unexplained weight loss, aching muscles, and abnormal pulmonary function. 

There is no cure for idiopathic pulmonary fibrosis, but treatment focuses on alleviating the symptoms and extending life. Oxygen therapy and lung transplants are sometimes used to treat the condition, as is medication. Drug classes often used to treat idiopathic pulmonary fibrosis are all other respiratory system products and protein kinase inhibitors.