Learn about the symptoms, treatments, and management of the most common types of blood cancer. Key takeaways: Blood cancer has three common forms Various medical procedures are available to treat these forms of the disease Early detection can make treatments more effective Over 1.3 million...
Read More... Aug 22, 2023Non-Hodgkin's Lymphoma (NHL)
Non-Hodgkin’s lymphoma refers to a group of blood cancers that develop in the lymphocytes, a type of white blood cells. More than 60,000 people in the United States are diagnosed with non-Hodgkin’s lymphoma each year, according to data from the Centers for Disease Control and Prevention.
It is more common than Hodgkin’s lymphoma, which occurs when cells in the lymph nodes start producing malignant cells. There are a number of different forms of non-Hodgkin’s lymphoma, the most common of which are B-cell lymphomas, such as large B-cell lymphoma or follicular lymphoma.
Symptoms of non-Hodgkin’s lymphoma may include swelling of the lymph nodes in the armpits, neck or groin, abdominal pain or swelling, chest pain, fatigue, fever, night sweats, and unexplained weight loss.
Risk factors for non-Hodgkin’s lymphoma include being over the age of 60; use of immunosuppressant drugs; having a weakened immune system; certain infections, such as HIV or Epstein-Bar virus; and exposure to certain chemicals.
Treatment of non-Hodgkin’s lymphoma will depend on the form of non-Hodgkin’s lymphoma but may include chemotherapy, radiation therapy, stem cell transplants, and medications to boost the immune system or deliver radioactive isotopes to tumors.
Drug classes commonly used to treat non-Hodgkin’s lymphomas are systemic corticosteroids, plain, protein kinase inhibitors, nitrogen mustard analogs, antineoplastic retinoids, interferons, alpha, folic acid analogs, colony-stimulating factors, other cytotoxic antibiotics, histone deacetylase inhibitors, other specific antirheumatics, antineoplastic monoclonal antibodies, and histone deacetylase inhibitors.
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Read More... Nov 04, 2017The US Food and Drug Administration (FDA) has given the nod to Yescarta (axicabtagene ciloleucel), the first cell-based gene therapy granted approval for the treatment of certain types of non-Hodgkin lymphoma (NHL) and only the second gene therapy to gain FDA approval. The drug is indicated for...
Read More... Oct 23, 2017A new treatment will soon be available for adults with relapsed follicular lymphoma, a slow-growing form of non-Hodgkin lymphoma, following the US Food and Drug Administration's (FDA) approval of Aliqopa (copanlisib). The drug was granted Accelerated Approval as it fills an unmet medical need....
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