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Urinary Tract Infection (UTI)

Urinary Tract Infection (UTI)

Urinary tract infections (UTIs) are among the most common infections and are defined as an infection of any part of the urinary tract, which includes the kidneys, ureters, bladder or urethra. They are normally caused by bacteria, but may also be viral or fungal. UTIs are the cause of nearly 10 million doctor visits annually, and around 20 percent of women will have a UTI at some point in their life.

Symptoms of UTIs include pain or a burning sensation while urinating, cloudy or bloody urine, groin or lower abdomen cramps, frequent urination, and a frequent feeling of needing to urinate. Risk factors that may increase the likelihood of a UTI developing include a history of UTIs, sexual activity, pregnancy, being female, urinary incontinence, kidney stones, an enlarged prostate, and old age.

Treatment of UTIs depends on the cause of the condition, as doctors will need to establish which organism is responsible for the infection. Medication is the most common treatment for UTIs. Drug classes commonly used to treat UTIs are urinary antibiotics and/or sulfonamides, irrigation solutions, citrates, penicillinase-sensitive penicillin antibiotics, penicillin and beta-lactamase inhibitor combination antibiotics, 1st generation cephalosporin antibiotics, sulfonamide and trimethoprim antibiotic combinations, fluoroquinolone antibiotics, tetracycline antibiotics, other urinary antiseptics, 2nd generation cephalosporin and cephamycin antibiotics, urinary analgesics and anesthetics, 3rd generation cephalosporin antibiotics, and other urinary antiseptics.

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Vabomere (meropenem and vaborbactam), an injection for treating adult patients with complicated urinary tract infections (cUTIs) will be available in the United States. by the end of 2017. Rempex Pharmaceuticals was granted approval for the antibiotic by the US Food and Drug Administration (FDA),...

Read More... Sep 12, 2017