Chronic granulomatous disease (CGD) is a rare hereditary immune deficiency disorder affecting certain white blood cells called phagocytes and preventing them from functioning correctly. This compromises the immune system and leaves patients with CGD more susceptible to bacterial, fungal, and other infections. 

Symptoms of CGD usually manifest in early childhood or infancy, although mild cases may not become apparent until adulthood. Patients with CGD may be more likely to develop other conditions, such as pneumonia, and infections of the lungs, skin, lymph nodes and liver. 

No cure exists for CGD, so treatment usually focuses on preventing infection and treating any infections that do take hold. Consequently, the drug classes used to treat patients with CGD depend on the nature of the infection. Commonly used drug classes include antibiotics, antifungals, and interferons, gamma.